diff --git a/opennebula/install.sh b/opennebula/install.sh
index bc85e4c0..c9bdb29b 100755
--- a/opennebula/install.sh
+++ b/opennebula/install.sh
@@ -3,7 +3,9 @@
 set -e
 
 reapply_patch() {
-	if ! patch -f --dry-run -F 0 -R $1 < $2 >/dev/null; then
+	if ! [[ -e $1 ]]; then
+		echo "$1 does not exist, OpenNebula is not installed"
+	elif ! patch -f --dry-run -F 0 -R $1 < $2 >/dev/null; then
 		already_applied=0
 		if ! patch --no-backup-if-mismatch -r - -F 0 -f $1 < $2; then
 			applied_ok=0
@@ -15,8 +17,13 @@ echo "Reapplying Vitastor patches to OpenNebula's oned.conf, vmm_execrc and down
 already_applied=1
 applied_ok=1
 reapply_patch /var/lib/one/remotes/datastore/downloader.sh /var/lib/one/remotes/datastore/vitastor/downloader-vitastor.sh.diff
-reapply_patch /etc/one/oned.conf /var/lib/one/remotes/datastore/vitastor/oned.conf.diff
 reapply_patch /etc/one/vmm_exec/vmm_execrc /var/lib/one/remotes/datastore/vitastor/vmm_execrc.diff
+if [[ -e /etc/one/oned.conf ]]; then
+	if ! /var/lib/one/remotes/datastore/vitastor/patch-oned-conf.py /etc/one/oned.conf; then
+		applied_ok=0
+		already_applied=0
+	fi
+fi
 if [[ "$already_applied" = 1 ]]; then
 	echo "OK: Vitastor OpenNebula patches are already applied"
 elif [[ "$applied_ok" = 1 ]]; then
diff --git a/opennebula/remotes/datastore/vitastor/patch-oned-conf.py b/opennebula/remotes/datastore/vitastor/patch-oned-conf.py
new file mode 100755
index 00000000..b1326d49
--- /dev/null
+++ b/opennebula/remotes/datastore/vitastor/patch-oned-conf.py
@@ -0,0 +1,115 @@
+#!/usr/bin/env python3
+# Patch /etc/one/oned.conf for Vitastor support
+# -s = also enable save.vitastor/restore.vitastor overrides
+
+import re
+import os
+import sys
+
+class Fixer:
+    save_restore = 0
+
+    def require_sub_cb(self, m, cb):
+        self.found = 1
+        return cb(m)
+
+    def require_sub(self, regexp, cb, text, error):
+        self.found = 0
+        new_text = re.sub(regexp, lambda m: self.require_sub_cb(m, cb), text)
+        if not self.found and error:
+            self.errors.append(error)
+        return new_text
+
+    def fix(self, oned_conf):
+        self.errors = []
+        self.kvm_found = 0
+        oned_conf = self.require_sub(r'((?:^|\n)[ \t]*VM_MAD\s*=\s*\[)([^\]]+)\]', lambda m: m.group(1)+self.fix_vm_mad(m.group(2))+']', oned_conf, 'VM_MAD not found')
+        if not self.kvm_found:
+            self.errors.append("VM_MAD[NAME=kvm].ARGUMENTS not found")
+        oned_conf = self.require_sub(r'((?:^|\n)[ \t]*TM_MAD\s*=\s*\[)([^\]]+)\]', lambda m: m.group(1)+self.fix_tm_mad(m.group(2))+']', oned_conf, 'TM_MAD not found')
+        oned_conf = self.require_sub(r'((?:^|\n)[ \t]*DATASTORE_MAD\s*=\s*\[)([^\]]+)\]', lambda m: m.group(1)+self.fix_datastore_mad(m.group(2))+']', oned_conf, 'DATASTORE_MAD not found')
+        if oned_conf[-1:] != '\n':
+            oned_conf += '\n'
+        if not re.compile(r'(^|\n)[ \t]*INHERIT_DATASTORE_ATTR\s*=\s*"VITASTOR_CONF"').search(oned_conf):
+            oned_conf += '\nINHERIT_DATASTORE_ATTR="VITASTOR_CONF"\n'
+        if not re.compile(r'(^|\n)[ \t]*INHERIT_DATASTORE_ATTR\s*=\s*"IMAGE_PREFIX"').search(oned_conf):
+            oned_conf += '\nINHERIT_DATASTORE_ATTR="IMAGE_PREFIX"\n'
+        if not re.compile(r'(^|\n)[ \t]*TM_MAD_CONF\s*=\s*\[[^\]]*NAME\s*=\s*"vitastor"').search(oned_conf):
+            oned_conf += ('\nTM_MAD_CONF = [\n'+
+                '    NAME = "vitastor", LN_TARGET = "NONE", CLONE_TARGET = "SELF", SHARED = "YES",\n'+
+                '    DS_MIGRATE = "NO", DRIVER = "raw", ALLOW_ORPHANS="format",\n'+
+                '    TM_MAD_SYSTEM = "ssh,shared", LN_TARGET_SSH = "SYSTEM", CLONE_TARGET_SSH = "SYSTEM",\n'+
+                '    DISK_TYPE_SSH = "FILE", LN_TARGET_SHARED = "NONE",\n'+
+                '    CLONE_TARGET_SHARED = "SELF", DISK_TYPE_SHARED = "FILE"\n'+
+                ']\n')
+        if not re.compile(r'(^|\n)[ \t]*DS_MAD_CONF\s*=\s*\[[^\]]*NAME\s*=\s*"vitastor"').search(oned_conf):
+            oned_conf += ('\nDS_MAD_CONF = [\n'+
+                '    NAME = "vitastor",\n'+
+                '    REQUIRED_ATTRS = "DISK_TYPE,BRIDGE_LIST",\n'+
+                '    PERSISTENT_ONLY = "NO",\n'+
+                '    MARKETPLACE_ACTIONS = "export"\n'+
+                ']\n')
+        return oned_conf
+
+    def fix_vm_mad(self, vm_mad_params):
+        if re.compile(r'\bNAME\s*=\s*"kvm"').search(vm_mad_params):
+            vm_mad_params = re.sub(r'\b(ARGUMENTS\s*=\s*")([^"]+)"', lambda m: m.group(1)+self.fix_vm_mad_args(m.group(2))+'"', vm_mad_params)
+            self.kvm_found = 1
+        return vm_mad_params
+
+    def fix_vm_mad_args(self, args):
+        args = self.fix_vm_mad_override(args, 'deploy')
+        if self.save_restore:
+            args = self.fix_vm_mad_override(args, 'save')
+            args = self.fix_vm_mad_override(args, 'restore')
+        return args
+
+    def fix_vm_mad_override(self, args, override):
+        m = re.compile(r'-l (\S+)').search(args)
+        if m and re.compile(override+'='+override+'.vitastor').search(m.group(1)):
+            return args
+        elif m and re.compile(override+'=').search(m.group(1)):
+            self.errors.append(override+"= is already overridden in -l option in VM_MAD[NAME=kvm].ARGUMENTS")
+            return args
+        elif m:
+            return self.require_sub(r'-l (\S+)', lambda m: '-l '+m.group(1)+','+override+'='+override+'.vitastor', args, '-l option not found in VM_MAD[NAME=kvm].ARGUMENTS')
+        else:
+            return args+' -l '+override+'='+override+'.vitastor'
+
+    def fix_tm_mad(self, params):
+        return self.require_sub(r'\b(ARGUMENTS\s*=\s*")([^"]+)"', lambda m: m.group(1)+self.fix_tm_mad_args('d', m.group(2), "TM_MAD")+'"', params, "TM_MAD.ARGUMENTS not found")
+
+    def fix_tm_mad_args(self, opt, args, v):
+        return self.require_sub('(-'+opt+r') (\S+)', lambda m: self.fix_tm_mad_arg(m), args, "-"+opt+" option not found in "+v+".ARGUMENTS")
+
+    def fix_tm_mad_arg(self, m):
+        a = m.group(2).split(',')
+        if 'vitastor' not in a:
+            a += [ 'vitastor' ]
+        return m.group(1)+' '+(','.join(a))
+
+    def fix_datastore_mad(self, params):
+        params = self.require_sub(r'\b(ARGUMENTS\s*=\s*")([^"]+)"', lambda m: m.group(1)+self.fix_tm_mad_args('d', m.group(2), "DATASTORE_MAD")+'"', params, "DATASTORE_MAD.ARGUMENTS not found")
+        return self.require_sub(r'\b(ARGUMENTS\s*=\s*")([^"]+)"', lambda m: m.group(1)+self.fix_tm_mad_args('s', m.group(2), "DATASTORE_MAD")+'"', params, "")
+
+fixer = Fixer()
+oned_conf_file = ''
+for arg in sys.argv[1:]:
+    if arg == '-s':
+        fixer.save_restore = 1
+    else:
+        oned_conf_file = arg
+        break
+if not oned_conf_file:
+    sys.stderr.write("USAGE: ./patch-oned-conf.py [-s] /etc/one/oned.conf\n-s means also enable save.vitastor/restore.vitastor overrides\n")
+    sys.exit(1)
+with open(oned_conf_file, 'r') as fd:
+    oned_conf = fd.read()
+new_conf = fixer.fix(oned_conf)
+if new_conf != oned_conf:
+    os.rename(oned_conf_file, oned_conf_file+'.bak')
+    with open(oned_conf_file, 'w') as fd:
+        fd.write(new_conf)
+if len(fixer.errors) > 0:
+    sys.stderr.write("ERROR: Failed to patch "+oned_conf_file+", patch it manually. Errors:\n- "+('\n- '.join(fixer.errors))+'\n')
+    sys.exit(1)